Genomic analysis of APP, PSEN1 and MAPT genes involved in the pathogenesis of Alzheimer’s disease
Isac, Maria Crina (2025), Genomic analysis of APP, PSEN1 and MAPT genes involved in the pathogenesis of Alzheimer’s disease, Cunoașterea Științifică, 4:4, 21-36, DOI: 10.58679/CS35521, https://www.cunoasterea.ro/genomic-analysis-of-app-psen1-and-mapt-genes/ Abstract Neurodegenerative diseases, such as Alzheimer’s disease or other forms of dementia, represent a major challenge for global public health, and understanding the genetic mechanisms involved is essential for the development of diagnostic and treatment strategies. This work aims to study three key genes involved in the pathogenesis of neurodegeneration: APP (Amyloid Precursor … Citeşte mai mult